Benefits that compound
Your O3 Blue Omega-3s restructure your cell membranes - making every cell in your body more fluid, responsive and alive, fundamentally renewing your biology over time.
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Ultimate O3 Blue Omega-3s
1,800mg of EPA (1,020mg) and DHA (780mg) per serving, plus DPA, in triglyceride form.
The complete family of long-chain omega-3s - EPA, DHA and DPA - in the form the body absorbs most readily.
Every batch is independently tested and verifiable for lipid concentration, oxidation and toxins. IFOS 5-Star Certified.
Sale price
Rs. 4,479.00
Regular price Rs. 4,943.00
Patron Price
Easy to swallow
Sleek and frictionless
Easy to digest
Fish gelatin based shell
Safe. Certified
cGMP. IFOS
Nutritional Information
Serving size: 2 Softgels (3.14g) | Servings per container: 30
| Nutrients | Amt/Cap | Amt/Serve | % RDA |
|---|---|---|---|
| Energy (kcal) | 11.75 | 23.5 | 1.2 |
| Total Fats (g) | 1.14 | 2.22 | 3.3 |
| Saturated Fats (g) | 0 | 0.01 | 0.04 |
| Trans Fats (g) | 0 | 0 | 0 |
| Protein (g) | 0.30 | 0.61 | 1.5 |
| Carbohydrates (g) | 0.13 | 0.26 | ** |
| Cholesterol (mg) | 1.4 | 2.8 | ** |
| Sodium (mg) | 0.02 | 0.05 | - |
| Composition | Amt/Cap | Amt/Serve | % RDA |
| Fish Oil (mg) | 1150 | 2300 | ** |
| EPA (mg) | 510 | 1020 | ** |
| DHA (mg) | 390 | 780 | ** |
| Rosemary extract (mg) | 1.5 | 3 | ** |
Ingredients
- Fish Oil (Wild Anchovies)
- Mixed Tocopherols (Natural, Non-GMO)
- Rosemary Extract (Natural, Non-GMO)
- Softgel (Fish Gelatin, Glycerin, Purified Water)
Allergen Information: Contains Fish
Suggested Dosage
1-2 softgel with meal. Consult a healthcare professional for personalised guidance.
For Optimal Absorption
Given O3 Blue Omega-3's natural triglyceride form and high-potency EPA+DHA concentration, pair your dose with a meal containing dietary fat.
If you take fiber supplements with meals, maintain a 2-hour gap for optimal absorption.
Coming Soon: The Āyu Dosage Quiz — a personalised recommendation based on your health goals.
Suitable for ages 13+. Teenagers with no specific health concerns may benefit from a more DHA-forward offering.
Complimentary savings on 2
Preserved under strict temperature and humidity control . Delivered within three days.
What O3 Blue can do for you
Zero shortcuts. Ultimate by design
Questions worth your attention
How long before I notice something?
It depends on where you are in the Omega-3 journey. If you've never supplemented before, your body is rebuilding from a deficit. Here's what consistent, daily intake of O3 Blue 1,800mg EPA + DHA serve looks like over time:
Hours 1–24
First Dose
Your body responds before you notice a thing.
Plasma EPA and DHA concentrations rise detectably within 4–6 hours of your first softgel.
Single-dose kinetics study, 2025
Specialized pro-resolving mediators — resolvins, protectins, and maresins — appear within 2–24 hours, activating your body's inflammation-resolution machinery.
Souza et al., Circulation Research, 2020
DHA lingers longer in plasma than EPA (half-life ~88 hours vs ~30 hours), building up faster in plasma pools.
Single-dose kinetics study, 12 men, 2025
You won't feel anything yet. That's expected.
Weeks 1–2
Silent Remodeling
Invisible changes. Measurable ones.
Platelet membranes (lifespan 8–10 days) begin incorporating EPA within the first week.
Faber et al., Journal of Nutrition, 2011
Your eicosanoid profile starts shifting — fewer pro-inflammatory signaling lipids, more anti-inflammatory EPA-derived series-3 prostaglandins.
By day 5, total plasma SPMs increase significantly and leukocyte behavior shifts toward pro-resolving function.
Schaller et al., Journal of the American Heart Association, 2020
Omega-3 Index barely moves — from ~4–5% to roughly 4.5–5.5%. Your body is accumulating substrate, not yet deploying it at scale.
Still nothing perceptible. Triglycerides, blood pressure, mood, cognition, skin, joints — all unchanged.
Weeks 3–4
Plasma Equilibrium
The first measurable shifts beneath the surface.
Fasting plasma phospholipid EPA+DHA approaches near-steady state.
Katan et al., Journal of Lipid Research, 1997; n=58
Omega-3 Index reaches ~5.5–6.5% from a 4% baseline — roughly 30–40% of the ultimate change.
Cao et al., 2006; Flock et al., JAHA, 2013
Triglyceride reductions of ~5–10% may be measurable via blood test (varies with baseline levels).
In individuals with elevated CRP, early CRP reductions may appear — one study found a 40.7% hs-CRP decrease after one month at 1.5 g/day.
Study in hypertensive patients with metabolic syndrome
Dry eye sufferers may notice modest symptom improvement beginning around day 30.
Bhargava et al., Eye & Contact Lens, 2016; n=256
Most people still feel nothing. Some with pre-existing anxiety or depression may notice subtle mood stabilization.
Weeks 5–8
Measurable Changes
Cardiovascular and skin markers begin moving.
Omega-3 Index reaches ~7–8%. Erythrocyte EPA increases ~300% and DHA ~42% from baseline.
Cao et al., 2006; participants at 2,160 mg/day
Cardiac tissue, highly correlated with red blood cell levels (r = 0.82), is accumulating EPA and DHA in parallel.
Harris et al., Circulation, 2004
Triglycerides show robust reductions — approximately 10–15% at 1,800 mg/day, with higher baselines yielding larger drops.
Skulas-Ray et al., 2011
Heart rate variability may begin improving at the upper end of this window, though modest gains may not reach significance until week 12.
Skulas-Ray et al., Psychosomatic Medicine, 2013
Skin improvements detectable — eczema patients may see improvement as early as week 2, psoriasis patients show measurable improvement by week 8.
Mirrahimi et al., 2023; Balbás et al., 2011
Depression scores significantly improved in clinical populations across multiple RCTs with 8-week endpoints.
ISNPR recommendation: minimum 8 weeks for assessing antidepressant response
Dry eye patients show improving tear break-up time and reduced tear osmolarity by 6 weeks.
Epitropoulos et al., Cornea, 2016; n=105
This is when many people first start noticing differences — skin texture, mood stability, less eye dryness.
Weeks 9–12
Therapeutic Range
The critical inflection point. Most biomarkers reach therapeutic levels.
Omega-3 Index likely reaches 8–9%, crossing into the cardioprotective zone.
Harris & von Schacky, Preventive Medicine, 2004; Walker et al., AJCN, 2019
Triglyceride reduction approaches its peak — approximately 15–20% at this dose.
AHA Science Advisory, Skulas-Ray et al., Circulation, 2019
Blood pressure reductions become established. Hypertensive individuals may see reductions of −4.51 mmHg systolic and −3.05 mmHg diastolic.
Miller et al., Am J Hypertension, 2014; 70 RCTs. Zhang et al., JAHA, 2022; 71 studies
Anxiety shows its clearest improvement — a 20% reduction in anxiety symptoms and 14% reduction in stimulated IL-6 in healthy subjects.
Kiecolt-Glaser et al., Brain, Behavior, and Immunity, 2011; n=68
Dry eye: 65% of omega-3 recipients show significant symptom improvement at 3 months vs 33% on placebo.
Bhargava et al., 2013; n=264. Epitropoulos et al., 2016
Joint health benefits first appear in the literature. Pain relief detectable at 1 month, growing over time.
Kremer, AJCN, 2000; 2025 Frontiers meta-analysis
Cerebral blood flow increases become measurable — enhanced perfusion during cognitive tasks.
Jackson et al., near-infrared spectroscopy study
The 12-week mark is where patience meets evidence. Most clinical effects become statistically detectable.
Months 4–6
Steady State
The body approaches equilibrium. The brain is just getting started.
Omega-3 Index plateaus at approximately 9–10% for most responders.
Flock et al., 2013; mean O3I ~9.5% after 5 months at 1,800 mg/day
Cardiac tissue well into enrichment — 110% increase in cardiac EPA+DHA documented after 6 months.
Harris et al., Circulation, 2004
Cognitive function shows its most consistent improvements. Episodic memory performance equivalent to ~7 years younger in healthy elderly.
Yurko-Mauro et al., 2010; n=485. Stonehouse et al., AJCN, 2013; n=176
Executive function, white matter integrity, gray matter volume, and neurovascular function all improved at 26 weeks.
Witte et al., 2,200 mg/day, ages 50–75
Skin hydration reaches robust, measurable improvement. Transepidermal water loss reduced.
Oyovwi et al., 2025; n=120
Resting heart rate reduction established — approximately −1.6 bpm overall, −2.5 bpm in those with baseline ≥69 bpm.
Mozaffarian et al., Circulation, 2005; 30 RCTs, n=1,678
Sleep quality improves — increased sleep efficiency, decreased sleep latency, reduced fragmentation.
Jackson et al., Nutrients, 2021; 26-week RCT, n=84
UV photoprotection: at higher doses, a 70% increase in sunburn threshold documented, with dermal EPA content rising 8-fold.
Rhodes et al., 1995; Pilkington et al., 2014
This is where most people describe feeling meaningfully different — sharper, calmer, better rested.
Beyond 6 Months
Deep Enrichment
The long game. Brain, joints, and cardiovascular protection deepen.
Brain DHA has a half-life of approximately 2.5 years. Full brain steady state takes years of uninterrupted supplementation.
Umhau et al., Journal of Lipid Research, 2009; PET imaging, n=14
Adipose tissue continues accumulating omega-3s beyond 12 months — at 6 months, adipose EPA was only 67% of the 12-month value.
Katan et al., 1997
Joint pain relief triples between 1 month and 6 months. Some RA patients on combined therapy could discontinue NSAIDs for 8+ weeks without disease flare.
2025 Frontiers meta-analysis; Kremer et al., 1995
Cognitive and neuroprotective benefits continue deepening, particularly in older adults and those with mild cognitive impairment.
Cardiovascular event reduction is a years-long outcome — the REDUCE-IT trial showed a 25% reduction in major adverse cardiovascular events over a median of 4.9 years.
Bhatt et al., NEJM, 2019; n=8,179 (4 g/day pure EPA)
Omega-3s are a long-term commitment. The longer you stay, the more your body has to work with.
Pregnancy & Lactation
A Distinct Timeline
For mothers, the stakes — and the evidence — are specific.
Supplementation starting by 12 weeks' gestation reduced preterm birth by 11% and early preterm birth by 42%.
Cochrane review, Middleton et al., 2018; 70 RCTs, 19,927 women
In women with low baseline omega-3 status, supplementation produced a 77% reduction in early preterm birth.
ORIP trial, Makrides et al., NEJM, 2019; n=5,486
Fetal DHA accretion accelerates dramatically in the third trimester — the fetus accumulates approximately 50–70 mg DHA per day during weeks 29–40.
Maternal EPA intake directly enhances DHA delivery to the fetus by upregulating all fatty acid transport proteins in the placenta.
Breast milk DHA content responds rapidly — changes are detectable within hours, peaking ~12 hours after ingestion.
LactMed database
Infants of supplemented mothers show improved visual acuity at 4 months and higher psychomotor development scores at 30 months.
Jensen et al., 2005
The dose is safe during pregnancy — the European Food Safety Authority considers up to 5 g/day safe for pregnant women.
EFSA; 2025 meta-analysis of 7 RCTs, n=9,957
The optimal dose identified for pregnancy outcomes was 500–1,000 mg/day with ≥500 mg DHA.
Individual response varies enormously — genetics, body weight, baseline omega-3 status, form(O3 Blue's superior rTG vs Ethyl esters) and whether you take capsules with a fat-containing meal all affect outcomes.
Testing your Omega-3 Index after 3 months is the only way to confirm your personal response.
At 1,800 mg/day standard serve of O3 Blue Omegas, the dose falls below the ≥2.7 g/day threshold many joint inflammation studies used. Joint benefits may be modest at this dose.
All timelines referenced are based on peer-reviewed literature at or near O3 Blue Omega-3s standard serve of 1,800 mg EPA+DHA daily.
All timelines referenced are based on peer-reviewed literature at or near 1,800 mg EPA+DHA daily — the serve strength of Ultimate O3 Blue. This is not medical advice. Consult your healthcare provider for guidance specific to your health.
How many O3 Blue softgels should I consume?
1-2 O3 Blue softgels a day is considered suitable for most healthy individuals.
For individuals seeking specific benefits, two softgels, or as recommended by a health practitioner.
It is important to note that once your body is fully replenished with Omega-3, incremental dosage does not deliver incremental benefits. Ask your Medical or Nutritional advisor to know more.
How does fruit of ayu maintain freshness of the O3 Blue Omega-3s on shelf?
Freshness can be measured by TOTOX — lower, the fresher. All batches of Fruit of Āyu Omega-3s undergo independent lipid analysis and freshness tests every 6 months.
Latest independent reports are published for respective batches for consumer's review and submitted to respective governing bodies in markets Fruit of Āyu operates in.
The entire supply chain of Fruit of Āyu Omega-3s is highly controlled and stored strictly under temperature and humidity controlled, pharma-specific ISO, GDP and GMP certified warehouses.
The only time your bottle of Omega-3s is exposed to temperatures above 25°C is during the last mile delivery: the 2–3 day courier to your door. Even during this transit, light does not touch your bottle of Ultimate O3 Blue Omega-3s.
What is DPA and Other Omega-3s? How much of these are available per serve?
DPA (docosapentaenoic acid) is the third major marine-sourced Omega-3.
What makes DPA distinct: your body can convert it into both EPA and DHA as needed, making it a biological reserve. Emerging research also points to independent roles in cardiovascular protection and tissue repair.
Per serve (Two O3 Blue softgels): ~79mg DPA, alongside ~78mg of other naturally occurring omega-3 fatty acids.
Note: Only EPA and DHA quantities are independently verified.
Do you guarantee 1800mg EPA+DHA per serve of fruit of ayu O3 Blue Omega-3s?
Yes.
Each serve delivers a minimum of 1800mg and up to 2200mg EPA+DHA. The exact figure for your bottle is published in its batch-specific independent report.
We fill to the higher end at manufacture so that the 1800mg floor holds throughout the full two-year shelf life — meaning even a bottle bought late in its lifecycle delivers the potency on the label.
Our strict storage and handling keep that potency intact across the full shelf life - so the bottle performs to label whether opened on day one or month twenty-four.
I am pregnant. Is fruit of ayu O3 Blue Omega-3s safe for me and my baby?
Yes.
- The short life-cycle of anchovies (O3 Blue's fish source) means minimal bioaccumulation of heavy metals.
- The oil is processed in Norway to EU pharmaceutical-grade purity standards.
- Our fish gelatin softgels are gentle on digestion, which matters when your body is already sensitive during pregnancy.
- Zero additives. Zero masking agents.
- DHA is the building block of fetal brain and retinal development. O3 Blue delivers 780mg of DHA per serve.
Consult your nutritionist or healthcare professional before starting any supplement during pregnancy. A holistic assessment ensures the benefits of Omega-3s do not interfere with any ongoing conditions or medications prescribed to you.
Will fruit of ayu O3 Blue Omega-3s give me fishy burps?
O3 Blue is one of the purest Omega-3 oils in the world, and we prove it by not adding any flavouring to mask rancidity or oxidation.
Take it with a meal that contains fat, and the chances of a fishy burp are virtually zero. And if you do get one, it won't be unpleasant.
We do not guarantee 'No fishy burps'.
Some ayu softgels feel soft, and a few are stuck together or to the bottle. Is this normal?
Yes - and it's a direct result of how the shell is made. It doesn't affect the oil, the dose, or its freshness.
Our softgel shell is pharma-grade fish gelatin, plasticised with glycerine and nothing else.
Fish gelatin has a naturally lower melting point than the bovine and porcine gelatins used in most mass-market supplements, and it stays softer. Firmness, in a softgel, is bought with added plasticisers and hardening agents. We chose not to use them.
In India's heat, that cleaner shell can turn slightly tacky, so capsules may cling to each other or to the bottle.
To separate them, press gently on the sides of the bottle or use the back of a spoon. The shells are more resilient than they feel.
I already eat fish, nuts, and eggs. Do I still need fruit of ayu O3 Blue Omega-3s?
- If you eat fatty fish like Bangda or Rawas regularly
- Include walnuts, flaxseeds, and omega-3 enriched eggs in your diet
- You eat a balanced diet
- You sleep well
- and you have no specific health concerns
You're doing well. You may not need fruit of ayu Ultimate O3 Blue Omega-3s.
Who is fruit of ayu O3 Blue Omega-3s not for?
O3 Blue is a fish-derived, high-potency Omega-3. It may not be the right fit if:
- You have a fish allergy.
- You follow a vegetarian or vegan diet - both the oil and the softgel are fish-based.
- You take blood-thinning medication or have surgery scheduled - high-dose Omega-3 can influence clotting, so speak with your doctor first.
- A healthcare professional has advised you to limit your Omega-3 intake.
- O3 Blue is formulated for adults. For children, consult a paediatrician.
If you're pregnant or breastfeeding, O3 Blue is well-suited - see the question above for the detail.
Some of the cited research used higher doses than one serving of O3 Blue. Why?
Some of the trials were designed to change hard outcomes in people who were already facing an adverse condition. We cite them because they establish the mechanism and the direction.
REDUCE-IT is the exception at 4g of purified EPA, prescribed to patients already on statins. We printed the trial dosage too so you may compare.
If you are managing a diagnosed condition, the dose is a decision for your doctor and not for a label.
Pure Omega-3s
Unique research driven formulation
Crafted for Indians
Crafted for outliers
Ultimate O3 Blue Omega-3s
Rs. 4,943.00
Rs. 4,479.00